Achaogen(美國(guó))

Achaogen

美國(guó)Achaogenwww.achaogen.com2002年，羅姆斯伯格的實(shí)驗(yàn)室剛開(kāi)始獲得以上結(jié)果時(shí)，他就發(fā)現(xiàn)了一種潛在的藥物——能和抗生素一起服用的小分子藥物，該藥物可以阻止LexA受到剪切。他與兩個(gè)合伙人毫不費(fèi)力就籌集到1500萬(wàn)美元，開(kāi)辦了一家名叫Achaogen的公司(“Achao”的意思是“抵制混亂”— —并由一位投資者添加上“gen”，因?yàn)槊Q中具有這個(gè)后綴的公司，其發(fā)展往往會(huì)一帆風(fēng)順)。Achaogen(a-KAY-o-jen)developssmallmoleculetherapeuticstotreatmulti-drugresistantbacterialinfections,aseriousunmetmedicalneedcausinghundredsofthousandsofdeathsworldwideeachyear.Achaogenisdevelopingnext-generationaminoglycosides:“neoglycosides”—adesignationthatreflectstheirlineageandconveystheirnovelty.Achaogen’sleadneoglycosidesdisplaybroad-spectrumactivityagainstmanyresistantbacteriathatcausesystemicinfections,includingK.pneumoniae,E.coliandMRSA.Ourworld-classteamhasledorparticipatedinthedevelopmentofseveralapprovedand/orlate-stageantibacterialcompounds,andourscientificadvisorsincludeU.