MyoKardia(美國(guó))

MyoKardia

MyoKardiawww.myokardia.comMyoKardiaisdedicatedtorevolutionizingthetreatmentofcardiovasculardisease.Thecompany'sfirstprogramsincludehypertrophicanddilatedcardiomyopathy(HCMandDCM),whichtogetherafflicta pproximately1millionpeopleintheUnitedStates,andforwhichnonoveltherapeuticshavebeenbroughttomarketinoveradecade.TargetingDiseaseattheSourceMyoKardia'sproprietarydrugdiscoveryplatformbringstogetheradvancesfromthefieldsofcardiovasculargenomicsandheartmusclebiologytoenableitsscientiststotargetcertainheartdisease'atitssource.'Abnormalitiesinthebasicunitofheartmuscle,calledthesarcomeres,havebeenidentifiedasthedrivingcauseforavarietyofheartdisease,andthemostcommoncauseofhypertrophicanddilatedcardiomyopathy.Mutationsintheproteinsofthesarcomerecausediseasebyrenderingthemuscleeither'hyper'or'hypo'contractile.Develo