Sangamo(美國)

Sangamo BioSciences

美國SangamoBioScienceswww.sangamo.comSangamoBioSciences,公司(Nasdaq:SGMO)是鋅指核酸酶研究領域的先鋒。SigmaLifeScience是其合作伙伴，因而是已獲驗證的含ZFN技術研究試劑的來源 Sangamoisaclinicalstagebiopharmaceuticalcompanyfocusedontheresearch,deve lopmentandcommercializationofengineeredDNA-bindingproteinsforthedevelopmentofnoveltherapeuticstrategiesforunmetmedicalneeds.Weareworldwideleadersinthedevelopmentofaproprietarytechnologyplatformthatenablesspecificregulationofgeneexpressionandgenemodification.Thebasisofthisplatformisanaturallyoccurringclassoftranscriptionfactors,zincfingerDNA-bindingproteins(ZFPs)whichwecanengineertodrivedesiredtherapeuticoutcomes.EngineeredZFPscanbelinkedtofunctionaldomainsthatnormallyactivateorrepressgeneexpressiontocreateZFPtranscriptionfactors(ZFPTFs)capableofturninggenesonoroff.WecanalsolinkZFPstonucleasedomainstocreatezincfingernucle